Suffering from obesity?
Thinking of losing some kilos through medication, then go for GLP-1 therapies. They are widely used for weight loss because they reduce appetite and slow digestion, helping people shed excess fat.
But the one challenge with GLP-1 treatment is that the body not only loses fat but also lean muscle.
This is where creatine is the highlight.
Known for supporting strength and energy at the cellular level, creatine helps preserve and build muscle mass.
When used in conjunction with GLP-1 therapy, creatine may help counteract muscle loss, enabling individuals to maintain their strength and metabolic health while still benefiting from the weight-reducing effects of GLP-1.
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Why GLP-1 Users Risk Muscle Loss
GLP-1 medications, such as Ozempic, Wegovy, and Mounjaro, work by reducing appetite and slowing down digestion.
That’s great for cutting calories, but it often means you’re not eating enough protein or getting enough overall nutrition.
We must believe that fat loss is beneficial, but losing muscle along the way can have unintended consequences.
Less protein + less energy = your body taps into muscle tissue for fuel.
Why does this matter?
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Muscle loss slows metabolism, making it more challenging to maintain weight loss in the long term.
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Lower strength means workouts feel harder and less effective.
- Less lean mass = less daily energy and vitality.
Read more: Creatine for Women Over 40: The Secret to Stronger Muscles, Bones & Lasting Energy
How Creatine Preserves Lean Muscle
Boosts ATP Production for Energy
Creatine fuels your muscle cells by regenerating ATP, your body’s energy currency. On a low-calorie diet, this boost helps you push through workouts without feeling drained.
Reduces Muscle Protein Breakdown
Studies show that creatine reduces the breakdown of lean tissue, especially in calorie-deficient diets. When paired with HMB (as in GLDN Root Creatine), the effect is even more substantial, keeping muscle protected while fat is burned.
Supports Muscle Recovery
Ever feel wiped after a workout while on GLP-1 therapy?
Creatine helps reduce soreness and speeds up recovery, allowing you to stay consistent with your exercise routine.
Read more: Creatine for Women: Powder vs. Capsules—Which Should You Take?
Enhances Strength and Endurance
Even during weight loss, creatine helps maintain your ability to lift, tone, and stay active, which is critical for preserving lean muscle on GLP-1 therapy.
How to Use Creatine During GLP-1 Therapy
Dosage
Take 5 grams daily. No loading phase is necessary.
Timing
Anytime works; consistency matters more than timing. Many prefer post-workout or with meals.
Hydration
Creatine draws water into your muscle cells, so aim for 2–3 liters of water per day for optimal results.
Read more: The Best Creatine for Women: Top Types, Benefits & Myths Busted
Why GLDN Root Creatine + HMB Is Ideal for GLP-1 Users
GLP-1 therapy is an incredible tool for weight loss, but muscle preservation is key to keeping your results and your strength for the long haul.
Adding creatine provides your body with the necessary backup, increased energy, reduced muscle breakdown, and improved recovery.
Pair it with smart nutrition and strength training, and you’ll keep your metabolism strong while GLP-1 does its job.
Protect your progress, try GLDN Root Creatine + HMB today.
Reference:
- https://www.webmd.com/diet/calorie-deficit
- https://www.modern-medical-spa.com/post/maximizing-health-on-glp-1-medications-the-role-of-weight-training-protein-and-creatine
- https://www.compassindy.com/2025/07/creatine-prevents-muscles-loss-when-taking-glp-1-meds/
- https://hydrow.com/blog/how-to-combat-muscle-loss-while-taking-glp-1s/ https://www.medscape.com/viewarticle/can-creatine-play-positive-role-obesity-treatment-2025a1000gs8
